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Interferon-induced ISG15 pathway: an ongoing virus–host battle

ISG15 is an interferon (IFN)-induced ubiquitin-like protein that is conjugated to target proteins via the sequential action of three enzymes that are also induced by IFN. Unlike ubiquitin, which is highly conserved, the sequence of ISG15 varies between species. ISG15 conjugation inhibits many viruse...

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Detalles Bibliográficos
Autores principales: Zhao, Chen, Collins, Mark N., Hsiang, Tien-Ying, Krug, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622817/
https://www.ncbi.nlm.nih.gov/pubmed/23414970
http://dx.doi.org/10.1016/j.tim.2013.01.005