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Directional Release of Reovirus from the Apical Surface of Polarized Endothelial Cells

Bloodstream spread is a critical step in the pathogenesis of many viruses. However, mechanisms that promote viremia are not well understood. Reoviruses are neurotropic viruses that disseminate hematogenously to the central nervous system. Junctional adhesion molecule A (JAM-A) is a tight junction pr...

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Detalles Bibliográficos
Autores principales: Lai, Caroline M., Mainou, Bernardo A., Kim, Kwang S., Dermody, Terence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622924/
https://www.ncbi.nlm.nih.gov/pubmed/23572551
http://dx.doi.org/10.1128/mBio.00049-13