Complement Component 3C3 and C3a Receptor Are Required in Chitin-Dependent Allergic Sensitization to Aspergillus fumigatus but Dispensable in Chitin-Induced Innate Allergic Inflammation

Levels of the anaphylatoxin C3a are increased in patients with asthma compared with those in nonasthmatics and increase further still during asthma exacerbations. However, the role of C3a during sensitization to allergen is poorly understood. Sensitization to fungal allergens, such as Aspergillus fu...

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Detalles Bibliográficos
Autores principales: Roy, René M., Paes, Hugo C., Nanjappa, Som G., Sorkness, Ron, Gasper, David, Sterkel, Alana, Wüthrich, Marcel, Klein, Bruce S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622928/
https://www.ncbi.nlm.nih.gov/pubmed/23549917
http://dx.doi.org/10.1128/mBio.00162-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622928/
https://www.ncbi.nlm.nih.gov/pubmed/23549917
http://dx.doi.org/10.1128/mBio.00162-13

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