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Comparing Effects of BK Virus Agnoprotein and Herpes Simplex-1 ICP47 on MHC-I and MHC-II Expression

Background. Among human polyomaviruses, only BK virus (BKV) and JC virus (JCV) encode an agnoprotein upstream of VP1 on the viral late transcript. BKV agnoprotein is abundantly expressed late in the viral life cycle, but specific cellular and humoral immune responses are low or absent. We hypothesiz...

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Detalles Bibliográficos
Autores principales: Cioni, Michela, Mittelholzer, Christian, Wernli, Marion, Hirsch, Hans H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623393/
https://www.ncbi.nlm.nih.gov/pubmed/23606871
http://dx.doi.org/10.1155/2013/626823