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The internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment

The Ndc80 outer kinetochore complex plays a critical role in kinetochore–microtubule attachment, yet our understanding of the mechanism by which this complex interacts with spindle microtubules for timely and accurate chromosome segregation remains limited. Here we address this issue using an ndc80...

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Detalles Bibliográficos
Autores principales: Tang, Ngang Heok, Takada, Hirofumi, Hsu, Kuo-Shun, Toda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623634/
https://www.ncbi.nlm.nih.gov/pubmed/23427262
http://dx.doi.org/10.1091/mbc.E12-11-0817