Cargando…
The internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment
The Ndc80 outer kinetochore complex plays a critical role in kinetochore–microtubule attachment, yet our understanding of the mechanism by which this complex interacts with spindle microtubules for timely and accurate chromosome segregation remains limited. Here we address this issue using an ndc80...
Autores principales: | Tang, Ngang Heok, Takada, Hirofumi, Hsu, Kuo-Shun, Toda, Takashi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623634/ https://www.ncbi.nlm.nih.gov/pubmed/23427262 http://dx.doi.org/10.1091/mbc.E12-11-0817 |
Ejemplares similares
-
Alp7/TACC recruits kinesin-8–PP1 to the Ndc80 kinetochore protein for timely mitotic progression and chromosome movement
por: Tang, Ngang Heok, et al.
Publicado: (2015) -
Ndc80 Internal Loop Interacts with Dis1/TOG to Ensure Proper Kinetochore-Spindle Attachment in Fission Yeast
por: Hsu, Kuo-Shun, et al.
Publicado: (2011) -
Targeting Alp7/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast
por: Tang, Ngang Heok, et al.
Publicado: (2014) -
CDK-dependent phosphorylation of Alp7–Alp14 (TACC–TOG) promotes its nuclear accumulation and spindle microtubule assembly
por: Okada, Naoyuki, et al.
Publicado: (2014) -
MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formation
por: Tang, Ngang Heok, et al.
Publicado: (2015)