Doc2b promotes GLUT4 exocytosis by activating the SNARE-mediated fusion reaction in a calcium- and membrane bending–dependent manner

The glucose transporter GLUT4 plays a central role in maintaining body glucose homeostasis. On insulin stimulation, GLUT4-containing vesicles fuse with the plasma membrane, relocating GLUT4 from intracellular reservoirs to the cell surface to uptake excess blood glucose. The GLUT4 vesicle fusion rea...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Haijia, Rathore, Shailendra S., Davis, Eric M., Ouyang, Yan, Shen, Jingshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623638/
https://www.ncbi.nlm.nih.gov/pubmed/23427263
http://dx.doi.org/10.1091/mbc.E12-11-0810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623638/
https://www.ncbi.nlm.nih.gov/pubmed/23427263
http://dx.doi.org/10.1091/mbc.E12-11-0810

Ejemplares similares