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Doc2b promotes GLUT4 exocytosis by activating the SNARE-mediated fusion reaction in a calcium- and membrane bending–dependent manner
The glucose transporter GLUT4 plays a central role in maintaining body glucose homeostasis. On insulin stimulation, GLUT4-containing vesicles fuse with the plasma membrane, relocating GLUT4 from intracellular reservoirs to the cell surface to uptake excess blood glucose. The GLUT4 vesicle fusion rea...
Autores principales: | Yu, Haijia, Rathore, Shailendra S., Davis, Eric M., Ouyang, Yan, Shen, Jingshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623638/ https://www.ncbi.nlm.nih.gov/pubmed/23427263 http://dx.doi.org/10.1091/mbc.E12-11-0810 |
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