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In vivo analysis of human nucleoporin repeat domain interactions

The nuclear pore complex (NPC), assembled from ∼30 proteins termed nucleoporins (Nups), mediates selective nucleocytoplasmic trafficking. A subset of nucleoporins bear a domain with multiple phenylalanine–glycine (FG) motifs. As binding sites for transport receptors, FG Nups are critical in transloc...

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Detalles Bibliográficos
Autores principales: Xu, Songli, Powers, Maureen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623642/
https://www.ncbi.nlm.nih.gov/pubmed/23427268
http://dx.doi.org/10.1091/mbc.E12-08-0585