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Lynch syndrome related endometrial cancer: clinical significance beyond the endometrium

Lynch syndrome (LS), an autosomal dominant inherited cancer susceptibility syndrome, also known as hereditary non-polyposis colon cancer (HNPCC), is caused by a germline mutation in one of several DNA mismatch repair (MMR) genes. LS is the most common presentation of hereditary colorectal cancer (CR...

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Detalles Bibliográficos
Autores principales: Wang, Yiying, Wang, Yue, Li, Jie, Cragun, Janiel, Hatch, Kenneth, Chambers, Setsuko K, Zheng, Wenxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623651/
https://www.ncbi.nlm.nih.gov/pubmed/23531335
http://dx.doi.org/10.1186/1756-8722-6-22