Shining a Light on Dark Sequencing: Characterising Errors in Ion Torrent PGM Data

The Ion Torrent Personal Genome Machine (PGM) is a new sequencing platform that substantially differs from other sequencing technologies by measuring pH rather than light to detect polymerisation events. Using re-sequencing datasets, we comprehensively characterise the biases and errors introduced b...

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Detalles Bibliográficos
Autores principales: Bragg, Lauren M., Stone, Glenn, Butler, Margaret K., Hugenholtz, Philip, Tyson, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623719/
https://www.ncbi.nlm.nih.gov/pubmed/23592973
http://dx.doi.org/10.1371/journal.pcbi.1003031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623719/
https://www.ncbi.nlm.nih.gov/pubmed/23592973
http://dx.doi.org/10.1371/journal.pcbi.1003031

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