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Npc1 Acting in Neurons and Glia Is Essential for the Formation and Maintenance of CNS Myelin
Cholesterol availability is rate-limiting for myelination, and prior studies have established the importance of cholesterol synthesis by oligodendrocytes for normal CNS myelination. However, the contribution of cholesterol uptake through the endocytic pathway has not been fully explored. To address...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623760/ https://www.ncbi.nlm.nih.gov/pubmed/23593041 http://dx.doi.org/10.1371/journal.pgen.1003462 |