Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human–Neandertal Divergence

Ancient population structure shaping contemporary genetic variation has been recently appreciated and has important implications regarding our understanding of the structure of modern human genomes. We identified a ∼36-kb DNA segment in the human genome that displays an ancient substructure. The var...

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Detalles Bibliográficos
Autores principales: Gokcumen, Omer, Zhu, Qihui, Mulder, Lubbertus C. F., Iskow, Rebecca C., Austermann, Christian, Scharer, Christopher D., Raj, Towfique, Boss, Jeremy M., Sunyaev, Shamil, Price, Alkes, Stranger, Barbara, Simon, Viviana, Lee, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623772/
https://www.ncbi.nlm.nih.gov/pubmed/23593015
http://dx.doi.org/10.1371/journal.pgen.1003404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623772/
https://www.ncbi.nlm.nih.gov/pubmed/23593015
http://dx.doi.org/10.1371/journal.pgen.1003404

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