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Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human–Neandertal Divergence
Ancient population structure shaping contemporary genetic variation has been recently appreciated and has important implications regarding our understanding of the structure of modern human genomes. We identified a ∼36-kb DNA segment in the human genome that displays an ancient substructure. The var...
Autores principales: | Gokcumen, Omer, Zhu, Qihui, Mulder, Lubbertus C. F., Iskow, Rebecca C., Austermann, Christian, Scharer, Christopher D., Raj, Towfique, Boss, Jeremy M., Sunyaev, Shamil, Price, Alkes, Stranger, Barbara, Simon, Viviana, Lee, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623772/ https://www.ncbi.nlm.nih.gov/pubmed/23593015 http://dx.doi.org/10.1371/journal.pgen.1003404 |
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