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The expression and regulation of matrix metalloproteinase-3 is critically modulated by Porphyromonas gingivalis lipopolysaccharide with heterogeneous lipid A structures in human gingival fibroblasts

BACKGROUND: Porphyromonas gingivalis lipopolysaccharide (LPS) is a crucial virulence factor strongly associated with chronic periodontitis which is the primary cause of tooth loss in adults. It exhibits remarkable heterogeneity containing tetra-(LPS(1435/1449)) and penta-(LPS(1690)) acylated lipid A...

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Detalles Bibliográficos
Autores principales: Herath, Thanuja D K, Wang, Yu, Seneviratne, Chaminda J, Darveau, Richard P, Wang, Cun-Yu, Jin, Lijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623786/
https://www.ncbi.nlm.nih.gov/pubmed/23548063
http://dx.doi.org/10.1186/1471-2180-13-73