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The expression and regulation of matrix metalloproteinase-3 is critically modulated by Porphyromonas gingivalis lipopolysaccharide with heterogeneous lipid A structures in human gingival fibroblasts
BACKGROUND: Porphyromonas gingivalis lipopolysaccharide (LPS) is a crucial virulence factor strongly associated with chronic periodontitis which is the primary cause of tooth loss in adults. It exhibits remarkable heterogeneity containing tetra-(LPS(1435/1449)) and penta-(LPS(1690)) acylated lipid A...
Autores principales: | Herath, Thanuja D K, Wang, Yu, Seneviratne, Chaminda J, Darveau, Richard P, Wang, Cun-Yu, Jin, Lijian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623786/ https://www.ncbi.nlm.nih.gov/pubmed/23548063 http://dx.doi.org/10.1186/1471-2180-13-73 |
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