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Trans-packaging of human immunodeficiency virus type 1 genome into Gag virus-like particles in Saccharomyces cerevisiae

BACKGROUND: Yeast is recognized as a generally safe microorganism and is utilized for the production of pharmaceutical products, including vaccines. We previously showed that expression of human immunodeficiency virus type 1 (HIV-1) Gag protein in Saccharomyces cerevisiae spheroplasts released Gag v...

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Detalles Bibliográficos
Autores principales: Tomo, Naoki, Goto, Toshiyuki, Morikawa, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623794/
https://www.ncbi.nlm.nih.gov/pubmed/23530915
http://dx.doi.org/10.1186/1475-2859-12-28