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Hepatic autophagy is differentially regulated in periportal and pericentral zones - a general mechanism relevant for other tissues?

BACKGROUND: Liver zonation, the fact that metabolic pathways are spatially separated along the liver sinusoids, is fundamental for proper functioning of this organ. For example, glutamine synthesis from glutamate and ammonia is localized pericentrally in only 7% of the hepatocytes concentrically arr...

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Detalles Bibliográficos
Autores principales: Gebhardt, Rolf, Coffer, Paul J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623826/
https://www.ncbi.nlm.nih.gov/pubmed/23531205
http://dx.doi.org/10.1186/1478-811X-11-21