The NTD-CTD intersubunit interface plays a critical role in assembly and stabilization of the HIV-1 capsid

BACKGROUND: Lentiviruses exhibit a cone-shaped capsid composed of subunits of the viral CA protein. The intrinsic stability of the capsid is critical for HIV-1 infection, since both stabilizing and destabilizing mutations compromise viral infectivity. Structural studies have identified three intersu...

Descripción completa

Detalles Bibliográficos
Autores principales: Yufenyuy, Ernest L, Aiken, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623829/
https://www.ncbi.nlm.nih.gov/pubmed/23497318
http://dx.doi.org/10.1186/1742-4690-10-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623829/
https://www.ncbi.nlm.nih.gov/pubmed/23497318
http://dx.doi.org/10.1186/1742-4690-10-29

Ejemplares similares