Cargando…
The NTD-CTD intersubunit interface plays a critical role in assembly and stabilization of the HIV-1 capsid
BACKGROUND: Lentiviruses exhibit a cone-shaped capsid composed of subunits of the viral CA protein. The intrinsic stability of the capsid is critical for HIV-1 infection, since both stabilizing and destabilizing mutations compromise viral infectivity. Structural studies have identified three intersu...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623829/ https://www.ncbi.nlm.nih.gov/pubmed/23497318 http://dx.doi.org/10.1186/1742-4690-10-29 |