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Structural and Functional Role of INI1 and LEDGF in the HIV-1 Preintegration Complex
Integration of the HIV-1 cDNA into the human genome is catalyzed by the viral integrase (IN) protein. Several studies have shown the importance of cellular cofactors that interact with integrase and affect viral integration and infectivity. In this study, we produced a stable complex between HIV-1 i...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623958/ https://www.ncbi.nlm.nih.gov/pubmed/23593299 http://dx.doi.org/10.1371/journal.pone.0060734 |