Structural and Functional Role of INI1 and LEDGF in the HIV-1 Preintegration Complex

Integration of the HIV-1 cDNA into the human genome is catalyzed by the viral integrase (IN) protein. Several studies have shown the importance of cellular cofactors that interact with integrase and affect viral integration and infectivity. In this study, we produced a stable complex between HIV-1 i...

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Detalles Bibliográficos
Autores principales: Maillot, Benoit, Lévy, Nicolas, Eiler, Sylvia, Crucifix, Corinne, Granger, Florence, Richert, Ludovic, Didier, Pascal, Godet, Julien, Pradeau-Aubreton, Karine, Emiliani, Stéphane, Nazabal, Alexis, Lesbats, Paul, Parissi, Vincent, Mely, Yves, Moras, Dino, Schultz, Patrick, Ruff, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623958/
https://www.ncbi.nlm.nih.gov/pubmed/23593299
http://dx.doi.org/10.1371/journal.pone.0060734

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