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Intratumoral peptide injection enhances tumor cell antigenicity recognized by cytotoxic T lymphocytes: a potential option for improvement in antigen-specific cancer immunotherapy

Antigen-specific cancer immunotherapy is a promising strategy for improving cancer treatment. Recently, many tumor-associated antigens and their epitopes recognized by cytotoxic T lymphocytes (CTLs) have been identified. However, the density of endogenously presented antigen-derived peptides on tumo...

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Detalles Bibliográficos
Autores principales: Nobuoka, Daisuke, Yoshikawa, Toshiaki, Takahashi, Mari, Iwama, Tatsuaki, Horie, Kazutaka, Shimomura, Manami, Suzuki, Shiro, Sakemura, Noriko, Nakatsugawa, Munehide, Sadamori, Hiroshi, Yagi, Takahito, Fujiwara, Toshiyoshi, Nakatsura, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624010/
https://www.ncbi.nlm.nih.gov/pubmed/23143746
http://dx.doi.org/10.1007/s00262-012-1366-6