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B-cell targeted therapeutics in clinical development

B lymphocytes are the source of humoral immunity and are thus a critical component of the adaptive immune system. However, B cells can also be pathogenic and the origin of disease. Deregulated B-cell function has been implicated in several autoimmune diseases, including systemic lupus erythematosus,...

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Detalles Bibliográficos
Autores principales: Blüml, Stephan, McKeever, Kathleen, Ettinger, Rachel, Smolen, Josef, Herbst, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624127/
https://www.ncbi.nlm.nih.gov/pubmed/23566679
http://dx.doi.org/10.1186/ar3906