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B-cell targeted therapeutics in clinical development
B lymphocytes are the source of humoral immunity and are thus a critical component of the adaptive immune system. However, B cells can also be pathogenic and the origin of disease. Deregulated B-cell function has been implicated in several autoimmune diseases, including systemic lupus erythematosus,...
Autores principales: | Blüml, Stephan, McKeever, Kathleen, Ettinger, Rachel, Smolen, Josef, Herbst, Ronald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624127/ https://www.ncbi.nlm.nih.gov/pubmed/23566679 http://dx.doi.org/10.1186/ar3906 |
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