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Neutral Sphingomyelinase 2 (nSMase2)-dependent Exosomal Transfer of Angiogenic MicroRNAs Regulate Cancer Cell Metastasis

The release of humoral factors between cancer cells and the microenvironmental cells is critical for metastasis; however, the roles of secreted miRNAs in non-cell autonomous cancer progression against microenvironmental cells remain largely unknown. Here, we demonstrate that the neutral sphyngomyeli...

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Detalles Bibliográficos
Autores principales: Kosaka, Nobuyoshi, Iguchi, Haruhisa, Hagiwara, Keitaro, Yoshioka, Yusuke, Takeshita, Fumitaka, Ochiya, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624465/
https://www.ncbi.nlm.nih.gov/pubmed/23439645
http://dx.doi.org/10.1074/jbc.M112.446831