Sensing of Bacterial Type IV Secretion via the Unfolded Protein Response

Host cytokine responses to Brucella abortus infection are elicited predominantly by the deployment of a type IV secretion system (T4SS). However, the mechanism by which the T4SS elicits inflammation remains unknown. Here we show that translocation of the T4SS substrate VceC into host cells induces p...

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Detalles Bibliográficos
Autores principales: de Jong, Maarten F., Starr, Tregei, Winter, Maria G., den Hartigh, Andreas B., Child, Robert, Knodler, Leigh A., van Dijl, Jan Maarten, Celli, Jean, Tsolis, Renée M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624511/
https://www.ncbi.nlm.nih.gov/pubmed/23422410
http://dx.doi.org/10.1128/mBio.00418-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624511/
https://www.ncbi.nlm.nih.gov/pubmed/23422410
http://dx.doi.org/10.1128/mBio.00418-12

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