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Sensing of Bacterial Type IV Secretion via the Unfolded Protein Response
Host cytokine responses to Brucella abortus infection are elicited predominantly by the deployment of a type IV secretion system (T4SS). However, the mechanism by which the T4SS elicits inflammation remains unknown. Here we show that translocation of the T4SS substrate VceC into host cells induces p...
Autores principales: | de Jong, Maarten F., Starr, Tregei, Winter, Maria G., den Hartigh, Andreas B., Child, Robert, Knodler, Leigh A., van Dijl, Jan Maarten, Celli, Jean, Tsolis, Renée M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624511/ https://www.ncbi.nlm.nih.gov/pubmed/23422410 http://dx.doi.org/10.1128/mBio.00418-12 |
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