Chemical Nature and Reaction Mechanisms of the Molybdenum Cofactor of Xanthine Oxidoreductase

Xanthine oxidoreductase (XOR), a complex flavoprotein, catalyzes the metabolic reactions leading from hypoxanthine to xanthine and from xanthine to urate, and both reactions take place at the molybdenum cofactor. The enzyme is a target of drugs for therapy of gout or hyperuricemia. We review the che...

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Detalles Bibliográficos
Autores principales: Okamoto, Ken, Kusano, Teruo, Nishino, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624778/
https://www.ncbi.nlm.nih.gov/pubmed/23116398
http://dx.doi.org/10.2174/1381612811319140010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624778/
https://www.ncbi.nlm.nih.gov/pubmed/23116398
http://dx.doi.org/10.2174/1381612811319140010

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