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An approximate Bayesian approach for mapping paired-end DNA reads to a reference genome

Summary: Many high-throughput sequencing experiments produce paired DNA reads. Paired-end DNA reads provide extra positional information that is useful in reliable mapping of short reads to a reference genome, as well as in downstream analyses of structural variations. Given the importance of paired...

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Detalles Bibliográficos
Autores principales: Shrestha, Anish Man Singh, Frith, Martin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624798/
https://www.ncbi.nlm.nih.gov/pubmed/23413433
http://dx.doi.org/10.1093/bioinformatics/btt073