Cargando…
Systematic parameter estimation in data-rich environments for cell signalling dynamics
Motivation: Computational models of biological signalling networks, based on ordinary differential equations (ODEs), have generated many insights into cellular dynamics, but the model-building process typically requires estimating rate parameters based on experimentally observed concentrations. New...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624804/ https://www.ncbi.nlm.nih.gov/pubmed/23426255 http://dx.doi.org/10.1093/bioinformatics/btt083 |