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Systematic parameter estimation in data-rich environments for cell signalling dynamics

Motivation: Computational models of biological signalling networks, based on ordinary differential equations (ODEs), have generated many insights into cellular dynamics, but the model-building process typically requires estimating rate parameters based on experimentally observed concentrations. New...

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Detalles Bibliográficos
Autores principales:	Nim, Tri Hieu, Luo, Le, Clément, Marie-Véronique, White, Jacob K., Tucker-Kellogg, Lisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624804/ https://www.ncbi.nlm.nih.gov/pubmed/23426255 http://dx.doi.org/10.1093/bioinformatics/btt083

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