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Measuring guide-tree dependency of inferred gaps in progressive aligners

Motivation: Multiple sequence alignments are generally reconstructed using a progressive approach that follows a guide-tree. During this process, gaps are introduced at a cost to maximize residue pairing, but it is unclear whether inferred gaps reflect actual past events of sequence insertions or de...

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Detalles Bibliográficos
Autores principales: Capella-Gutiérrez, Salvador, Gabaldón, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624810/
https://www.ncbi.nlm.nih.gov/pubmed/23435067
http://dx.doi.org/10.1093/bioinformatics/btt095