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Measuring guide-tree dependency of inferred gaps in progressive aligners
Motivation: Multiple sequence alignments are generally reconstructed using a progressive approach that follows a guide-tree. During this process, gaps are introduced at a cost to maximize residue pairing, but it is unclear whether inferred gaps reflect actual past events of sequence insertions or de...
Autores principales: | Capella-Gutiérrez, Salvador, Gabaldón, Toni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624810/ https://www.ncbi.nlm.nih.gov/pubmed/23435067 http://dx.doi.org/10.1093/bioinformatics/btt095 |
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