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Hepatic veno-occlusive disease resulting in tacrolimus toxicity after allogeneic hematopoietic stem cell transplantation

Tacrolimus is a widely used immunosuppressive agent for the prophylaxis of graft-versus-host disease in allogeneic hematopoietic stem cell transplantation (HSCT). Since tacrolimus is primarily metabolized by the liver, hepatic dysfunction may affect its metabolism. Hepatic veno-occlusive disease (VO...

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Detalles Bibliográficos
Autores principales: Shin, Seung-Hwan, Yahng, Seung-Ah, Yoon, Jae-Ho, Lee, Sung-Eun, Cho, Byung-Sik, Kim, Yoo-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625009/
https://www.ncbi.nlm.nih.gov/pubmed/23589797
http://dx.doi.org/10.5045/br.2013.48.1.55