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A novel post-transcriptional role for ubiquitin in the differential regulation of MHC class I allotypes()

By providing ligands for Cytotoxic T-Lymphocytes (CTL) as well as Natural Killer (NK) cells, the HLA-A/B/C MHC class I molecules (MHC-I) play a central role in both innate and adaptive immunity. In addition to CTL-mediated recognition of MHC-peptide complexes, cell surface expression of MHC-I is clo...

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Detalles Bibliográficos
Autores principales: Cano, Florencia, Lehner, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625108/
https://www.ncbi.nlm.nih.gov/pubmed/23140835
http://dx.doi.org/10.1016/j.molimm.2012.10.015