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Recombinant Human Growth Hormone and Rosiglitazone for Abdominal Fat Accumulation in HIV-Infected Patients with Insulin Resistance: A Randomized, Double-Blind, Placebo-Controlled, Factorial Trial

BACKGROUND: Recombinant human growth hormone (rhGH) reduces visceral adipose tissue (VAT) volume in HIV-infected patients but can worsen glucose homeostasis and lipoatrophy. We aimed to determine if adding rosiglitazone to rhGH would abrogate the adverse effects of rhGH on insulin sensitivity (SI) a...

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Detalles Bibliográficos
Autores principales: Glesby, Marshall J., Albu, Jeanine, Chiu, Ya-Lin, Ham, Kirsis, Engelson, Ellen, He, Qing, Muthukrishnan, Varalakshmi, Ginsberg, Henry N., Donovan, Daniel, Ernst, Jerry, Lesser, Martin, Kotler, Donald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625151/
https://www.ncbi.nlm.nih.gov/pubmed/23593417
http://dx.doi.org/10.1371/journal.pone.0061160