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Cyclic-AMP Mediated Regulation of ABCB mRNA Expression in Mussel Haemocytes
BACKGROUND: The multixenobiotic resistance system (MXR) allows aquatic organisms to cope with their habitat despite high pollution levels by over-expressing membrane and intracellular transporters, including the P-glycoprotein (Pgp). In mammals transcription of the ABCB1 gene encoding Pgp is under c...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625153/ https://www.ncbi.nlm.nih.gov/pubmed/23593491 http://dx.doi.org/10.1371/journal.pone.0061634 |