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Cyclic-AMP Mediated Regulation of ABCB mRNA Expression in Mussel Haemocytes

BACKGROUND: The multixenobiotic resistance system (MXR) allows aquatic organisms to cope with their habitat despite high pollution levels by over-expressing membrane and intracellular transporters, including the P-glycoprotein (Pgp). In mammals transcription of the ABCB1 gene encoding Pgp is under c...

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Detalles Bibliográficos
Autores principales: Franzellitti, Silvia, Fabbri, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625153/
https://www.ncbi.nlm.nih.gov/pubmed/23593491
http://dx.doi.org/10.1371/journal.pone.0061634