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Acute Toxicity of Amorphous Silica Nanoparticles in Intravenously Exposed ICR Mice
This study aimed to evaluate the acute toxicity of intravenously administrated amorphous silica nanoparticles (SNPs) in mice. The lethal dose, 50 (LD(50)), of intravenously administrated SNPs was calculated in mice using Dixon's up-and-down method (262.45±33.78 mg/kg). The acute toxicity was ev...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625170/ https://www.ncbi.nlm.nih.gov/pubmed/23593469 http://dx.doi.org/10.1371/journal.pone.0061346 |