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Acute Toxicity of Amorphous Silica Nanoparticles in Intravenously Exposed ICR Mice

This study aimed to evaluate the acute toxicity of intravenously administrated amorphous silica nanoparticles (SNPs) in mice. The lethal dose, 50 (LD(50)), of intravenously administrated SNPs was calculated in mice using Dixon's up-and-down method (262.45±33.78 mg/kg). The acute toxicity was ev...

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Detalles Bibliográficos
Autores principales:	Yu, Yang, Li, Yang, Wang, Wen, Jin, Minghua, Du, Zhongjun, Li, Yanbo, Duan, Junchao, Yu, Yongbo, Sun, Zhiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625170/ https://www.ncbi.nlm.nih.gov/pubmed/23593469 http://dx.doi.org/10.1371/journal.pone.0061346

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