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Bone Morphogenetic Protein Type I Receptor Antagonists Decrease Growth and Induce Cell Death of Lung Cancer Cell Lines

Bone morphogenetic proteins (BMPs) are highly conserved morphogens that are essential for normal development. BMP-2 is highly expressed in the majority of non-small cell lung carcinomas (NSCLC) but not in normal lung tissue or benign lung tumors. The effects of the BMP signaling cascade on the growt...

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Detalles Bibliográficos
Autores principales: Langenfeld, Elaine, Hong, Charles C., Lanke, Gandhi, Langenfeld, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625205/
https://www.ncbi.nlm.nih.gov/pubmed/23593444
http://dx.doi.org/10.1371/journal.pone.0061256