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Periodic 17β-Estradiol Pretreatment Protects Rat Brain from Cerebral Ischemic Damage via Estrogen Receptor-β

Although chronic 17β-estradiol (E(2)) has been shown to be a cognition-preserving and neuroprotective agent in animal brain injury models, concern regarding its safety was raised by the failed translation of this phenomenon to the clinic. Previously, we demonstrated that a single bolus of E(2) 48 hr...

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Detalles Bibliográficos
Autores principales: Raval, Ami P., Borges-Garcia, Raquel, Javier Moreno, William, Perez-Pinzon, Miguel A., Bramlett, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625208/
https://www.ncbi.nlm.nih.gov/pubmed/23593292
http://dx.doi.org/10.1371/journal.pone.0060716