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Mutations in ap1b1 Cause Mistargeting of the Na(+)/K(+)-ATPase Pump in Sensory Hair Cells

The hair cells of the inner ear are polarized epithelial cells with a specialized structure at the apical surface, the mechanosensitive hair bundle. Mechanotransduction occurs within the hair bundle, whereas synaptic transmission takes place at the basolateral membrane. The molecular basis of the de...

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Detalles Bibliográficos
Autores principales: Clemens Grisham, Rachel, Kindt, Katie, Finger-Baier, Karin, Schmid, Bettina, Nicolson, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625210/
https://www.ncbi.nlm.nih.gov/pubmed/23593334
http://dx.doi.org/10.1371/journal.pone.0060866