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Amyloid-β Peptide on Sialyl-Lewis(X)-Selectin-Mediated Membrane Tether Mechanics at the Cerebral Endothelial Cell Surface

Increased deposition of amyloid-β peptide (Aβ) at the cerebral endothelial cell (CEC) surface has been implicated in enhancement of transmigration of monocytes across the brain blood barrier (BBB) in Alzheimer's disease (AD). In this study, quantitative immunofluorescence microscopy (QIM) and a...

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Detalles Bibliográficos
Autores principales: Askarova, Sholpan, Sun, Zhe, Sun, Grace Y., Meininger, Gerald A., Lee, James C-M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625223/
https://www.ncbi.nlm.nih.gov/pubmed/23593361
http://dx.doi.org/10.1371/journal.pone.0060972