The L-Cysteine Desulfurase NFS1 Is Localized in the Cytosol where it Provides the Sulfur for Molybdenum Cofactor Biosynthesis in Humans

In humans, the L-cysteine desulfurase NFS1 plays a crucial role in the mitochondrial iron-sulfur cluster biosynthesis and in the thiomodification of mitochondrial and cytosolic tRNAs. We have previously demonstrated that purified NFS1 is able to transfer sulfur to the C-terminal domain of MOCS3, a c...

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Detalles Bibliográficos
Autores principales: Marelja, Zvonimir, Mullick Chowdhury, Mita, Dosche, Carsten, Hille, Carsten, Baumann, Otto, Löhmannsröben, Hans-Gerd, Leimkühler, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625234/
https://www.ncbi.nlm.nih.gov/pubmed/23593335
http://dx.doi.org/10.1371/journal.pone.0060869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625234/
https://www.ncbi.nlm.nih.gov/pubmed/23593335
http://dx.doi.org/10.1371/journal.pone.0060869

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