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PPARδ Agonist GW501516 Inhibits PDGF-Stimulated Pulmonary Arterial Smooth Muscle Cell Function Related to Pathological Vascular Remodeling

Pulmonary arterial hypertension (PAH) is a severe and progressive disease, a key feature of which is pulmonary vascular remodeling. Growth factors, cytokines, and lipid mediators are involved in this remodeling process. Recent reports suggest that the peroxisome proliferator-activated receptors (PPA...

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Detalles Bibliográficos
Autores principales: Liu, Guangjie, Li, Xuan, Li, Yan, Tang, Xin, Xu, Jie, Li, Ran, Hao, Peng, Sun, Yongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625582/
https://www.ncbi.nlm.nih.gov/pubmed/23607100
http://dx.doi.org/10.1155/2013/903947