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Peptidomic discovery of short open reading frame-encoded peptides in human cells

The amount of the transcriptome that is translated into polypeptides is of fundamental importance. We developed a peptidomic strategy to detect short ORF (sORF)-encoded polypeptides (SEPs) in human cells. We identified 90 SEPs, 86 of which are novel, the largest number of human SEPs ever reported. S...

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Detalles Bibliográficos
Autores principales: Slavoff, Sarah A., Mitchell, Andrew J., Schwaid, Adam G., Cabili, Moran N., Ma, Jiao, Levin, Joshua Z., Karger, Amir D., Budnik, Bogdan A., Rinn, John L., Saghatelian, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625679/
https://www.ncbi.nlm.nih.gov/pubmed/23160002
http://dx.doi.org/10.1038/nchembio.1120