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Loss of Telomere Protection: Consequences and Opportunities

Telomeres are repetitive sequences at the natural ends of linear eukaryotic chromosomes that protect these from recognition as chromosome breaks. Their ability to do so critically depends on the binding of sufficient quantities of functional shelterin, a six-unit protein complex with specific and cr...

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Detalles Bibliográficos
Autor principal: Jacobs, Jacqueline J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625723/
https://www.ncbi.nlm.nih.gov/pubmed/23596571
http://dx.doi.org/10.3389/fonc.2013.00088