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Loss of Telomere Protection: Consequences and Opportunities
Telomeres are repetitive sequences at the natural ends of linear eukaryotic chromosomes that protect these from recognition as chromosome breaks. Their ability to do so critically depends on the binding of sufficient quantities of functional shelterin, a six-unit protein complex with specific and cr...
Autor principal: | Jacobs, Jacqueline J. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625723/ https://www.ncbi.nlm.nih.gov/pubmed/23596571 http://dx.doi.org/10.3389/fonc.2013.00088 |
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