Quantitative assay for TALEN activity at endogenous genomic loci

Artificially designed nucleases such as zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) can induce a targeted DNA double-strand break at the specific target genomic locus, leading to the frameshift-mediated gene disruption. However, the assays for their acti...

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Detalles Bibliográficos
Autores principales: Hisano, Yu, Ota, Satoshi, Arakawa, Kazuharu, Muraki, Michiko, Kono, Nobuaki, Oshita, Kazuki, Sakuma, Tetsushi, Tomita, Masaru, Yamamoto, Takashi, Okada, Yasushi, Kawahara, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625863/
https://www.ncbi.nlm.nih.gov/pubmed/23616919
http://dx.doi.org/10.1242/bio.20133871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625863/
https://www.ncbi.nlm.nih.gov/pubmed/23616919
http://dx.doi.org/10.1242/bio.20133871

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